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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
27.27
Human Site:
S241
Identified Species:
50
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S241
P
A
L
C
T
L
L
S
H
D
F
F
R
N
D
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S241
P
A
L
C
T
L
L
S
H
D
F
F
R
N
D
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S241
P
A
L
C
T
L
L
S
H
E
F
F
R
N
D
Dog
Lupus familis
XP_537198
743
82483
S241
P
A
L
C
T
L
L
S
H
D
F
F
R
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
S241
P
A
L
S
T
L
L
S
H
D
F
F
R
N
D
Rat
Rattus norvegicus
Q5M9F8
807
89107
L258
R
P
N
P
A
R
F
L
Q
N
C
R
A
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
S860
P
A
L
R
T
L
L
S
H
D
F
F
R
N
D
Chicken
Gallus gallus
NP_001012613
698
77220
S240
L
S
E
E
L
I
A
S
R
L
V
P
L
L
L
Frog
Xenopus laevis
Q561M0
827
91284
C256
P
S
R
F
L
Q
N
C
R
S
P
G
G
F
F
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
T241
P
S
L
S
T
L
L
T
H
N
F
F
R
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
H227
F
R
E
Y
C
S
T
H
L
K
H
Q
N
T
K
Honey Bee
Apis mellifera
XP_001123124
613
70111
K158
G
G
L
E
C
L
C
K
F
K
D
L
T
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
P247
P
K
L
K
T
L
L
P
D
E
I
F
K
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
93.3
100
N.A.
93.3
0
N.A.
93.3
6.6
6.6
73.3
N.A.
0
13.3
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
20
13.3
93.3
N.A.
0
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
0
8
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
31
16
0
8
8
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
39
8
0
0
0
62
% D
% Glu:
0
0
16
16
0
0
0
0
0
16
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
8
0
8
0
54
62
0
8
16
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
54
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
8
0
16
0
0
8
0
8
% K
% Leu:
8
0
70
0
16
70
62
8
8
8
0
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
16
0
0
8
62
0
% N
% Pro:
70
8
0
8
0
0
0
8
0
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% Q
% Arg:
8
8
8
8
0
8
0
0
16
0
0
8
54
0
0
% R
% Ser:
0
24
0
16
0
8
0
54
0
8
0
0
0
8
0
% S
% Thr:
0
0
0
0
62
0
8
8
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _